张转，1986年生，籍贯陕西铜川，医药生物技术研究所助理教授。2008-2014年在中国科学院上海有机化学研究所攻读博士学位，从事细菌天然产物的生物合成研究。2014-2017年在中国科学院上海有机化学研究所担任研究助理。2017-2020年在美国加州大学洛杉矶分校进行博士后研究，主要研究真菌天然产物生物合成。2020年进入美国德克萨斯大学休斯顿健康科学中心进行博士后研究，从事抗真菌药物的研发。

基因组挖掘活性天然产物，解析其生物合成机制，通过生物技术手段促进其临床应用；开发反刍动物来源的共生真菌的研究方法，表征反刍动物共生真菌的代谢产物、研究其和宿主之间的免疫相互作用。

1. Lee Joon Kim#, Masao Ohashi#, Zhuan Zhang#, Dan Tan, Matthew Asay, Duilio Cascio, José A. Rodriguez, Yi Tang* and Hosea M. Nelson*. Prospecting for natural products by genome mining and microcrystal electron diffraction, Nature Chemical Biology, 2021, 17(8): 872-877. (IF= 16.290)

2. Zhuan Zhang, Yui Tamura, Mancheng Tang, Tianzhang Qiao, Michio Sato, Yoshihiro Otsu, Satoshi Sasamura, Masatoshi Taniguchi, Kenji Watanabe* and Yi Tang*. Biosynthesis of the Immunosuppressant (−)-FR901483, Journal of the American Chemical Society, 2020, 143(1): 132-136. (IF= 15.419)

3. Zhuan Zhang; Tianzhang Qiao; Kenji Watanabe* and Yi Tang*. Concise Biosynthesis of Phenylfuropyridones in Fungi, Angewandte Chemie International Edition, 2020, 59(45): 19889-19893. (IF= 13.522)

4. Zhuan Zhang; Cooper S. Jamieson; Yi-Lei Zhao; Dehai Li; Masao Ohashi*, K. N. Houk* and Yi Tang*. Enzyme-Catalyzed Inverse-Electron Demand Diels−Alder Reaction in the Biosynthesis of Antifungal Ilicicolin H, Journal of the American Chemical Society, 2019, 141(14): 5659-5663. (IF= 14.695)

5. Yu Hu#, Zhuan Zhang#, Yue Yin, Gong-Li Tang*. Directed Biosynthesis of Iso-aclacinomycins with Improved Anticancer Activity, Organic Letters, 2019, 22(1): 150-154. (IF= 6.091)

6. Zhuan Zhang#; Yu-Kang Gong#; Qiang Zhou; Yu Hu; Hong-Min Ma; Yong-Sheng Chen; Yasuhiro Igarashi; Lifeng Pan*; Gong-Li Tang*. Hydroxyl regioisomerization of anthracycline catalyzed by a four-enzyme cascade, Proceedings of the National Academy of Sciences of the United States of America,2017, 114(7): 1554-1559. (IF= 9.504)

7. Hong-min Ma#, Qiang Zhou#, Yu-Min Tang#, Zhuan-Zhang#, Yong-sheng Chen, Hai-Yan He, Hai-Xue Pan, Man-Cheng Tang, Ju-Fang -Gao, Sheng-Yin Zhao, Yasuhiro Igarashi, Gong-Li Tang*. Unconventional Origin and Hybrid System for Construction of Pyrrolopyrrole Moiety in Kosinostatin Biosynthesis, Cell Chemistry & Biology, 2013, 20(6): 796-805. (IF=5.218)