周家喜，1976年生，籍贯湖北鹤峰，干细胞生物学家，中国医学科学院血液病医院（中国医学科学院血液学研究所）研究员，博士生导师，协和学者特聘教授，国家杰出青年基金获得者。1998年从华中农业大学获得学士学位，2001年在中国农业科学院研究生院获得硕士学位，2004年在中国科学院动物研究所获得博士学位。2005-2010年先后在美国Stowers医学研究所和伊利诺伊大学进行博士后研究。2010年回国加入实验血液学国家重点实验室，2011年成为研究员。

主要研究生理和病理条件下巨核细胞和血小板的发生和功能改变，以及它们在各种血液病及相关疾病中的意义。同时探索利用多能干细胞规模化生产血小板用于输注的应用研究，开发血小板相关诊断和治疗系列产品。

1. Changlu Xu#, Jian He#, Hongtao Wang#, Yingnan Zhang#, Jing Wu#, Lu Zhao#, Yue Li, Jie Gao, Guangfeng Geng, Bingrui Wang, Xiaoyuan Chen, Zhaofeng Zheng, Biao Shen, Yang Zeng, Zhijie Bai, Hua Yang, Shujuan Shi, Fang Dong, Shihui Ma, Erlie Jiang, Tao Cheng, Yu Lan*, Jiaxi Zhou*, Bing Liu*, Lihong Shi*. Single-cell transcriptomic analysis identifies an immune-prone population in erythroid precursors during human ontogenesis. Nature Immunology. 2022 Jul;23(7):1109-1120. (IF=31.25)

2. Yiying Liu#, Jingjing Zhao , Yan Wang, Pei Su, Hongtao Wang, Cuicui Liu*, Jiaxixi Zhou*.Augmented Production of Platelets From Cord Blood With Euchromatic Histone Lysine Methyltransferase Inhibition. Stem Cells Trans Med. 2022 Jul 26;szac048. (IF= 7.655)

3. Cuicui Liu#, Dan Wu#, Meijuan Xia#, Minmin Li, Zhiqiang Sun, Biao Shen, Yiying Liu,Erlie Jiang, Hongtao Wang, Pei Su, Lihong Shi, Zhijian Xiao, Xiaofan Zhu, Wen Zhou,Qianfei Wang, Xin Gao*, Tao Cheng*,and Jiaxi Zhou* Characterization of Cellular Heterogeneity and an Immune Subpopulation of Human Megakaryocytes. Advanced Science. 2021 Aug;8(15):e2100921. (IF= 17.521)

4. Hongtao Wang#, Jian He#, Changlu Xu#, Xiaoyuan Chen#, Hua Yang#, Shujuan Shi, Cuicui Liu, Yang Zeng, Dan Wu, Zhijie Bai, Mengge Wang, Yuqi Wen, Pei Su, Meijuan Xia, Baiming Huang, Chunyu Ma,Lihong Bian, Yu Lan, Tao Cheng, Lihong Shi,* Bing Liu, * Jiaxi Zhou* Decoding Human Megakaryocyte Development .Cell Stem Cell. 2021 Mar 4;28(3):535-549.

5. Hongtao Wang#,, Mengge Wang#, Yuqi Wen#, Changlu Xu, Xiaoyuan Chen, Dan Wu, Pei Su, Wen Zhou, Tao Cheng, Lihong Shi*, Jiaxi Zhou* Biphasic Regulation of Mesenchymal Genes Controls Fate Switches During Hematopoietic Differentiation of Human Pluripotent Stem Cells. Advanced Science. 2020 Aug 19;7(20):2001019 (IF=24.633 F1000)

6. Yu Wang#,Hongtao Wang, Jiaojiao Guo, Jie Gao, Mengge Wang, Meijuan Xia, Yuqi Wen, Pei Su,Ming Yang, Mingyao Liu, Lihong Shi, Tao Cheng, Wen Zhou, * and Jiaxi Zhou,* LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation. Cell Reports. 2020 May 5;31(5):107600. (IF=9.423)

7. Jinhua Liu#, Yapu Li#, Jingyuan Tong#, Jie Gao, Qing Guo, Lingling Zhang, Bingrui Wang, Hui Zhao,Hongtao Wang, Erlie Jiang, Ryo Kurita, Yukio Nakamura, Osamu Tanabe, James Douglas Enge,Emery H. Bresnick, Jiaxi Zhou *& Lihong Shi* Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development. Nature Communications. 2018 Oct 22;9(1):4386. (IF=11.878)

8. Leisheng Zhang#, Hongtao Wang#,Cuicui Liu, Qingqing Wu, Pei Su, Dan Wu, Jiaojiao Guo, Wen Zhou,Yuanfu Xu, Lihong Shi, JiaxiZhou*. MSX2 Initiates and Accelerates Mesenchymal Stem/Stromal Cell Specification of hPSCs by Regulating TWIST1 and PRAME. Stem Cell Reports. 2018 Aug 14;11(2):497-513 (IF=5.499)

9. Hongtao Wang#, Cuicui Liu#, Xin Liu#, Mengge Wang, Dan Wu, Jie Gao, Pei Su, Tatsutoshi Nakahata,Wen Zhou, Yuanfu Xu, Lihong Shi, Feng Ma*, Jiaxi Zhou* MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryocyte Polyploidization and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1. Stem Cell Reports. 2018 Feb 13;10(2):447-460. (IF=5.499)

10.Wu Q#, Zhang L, Su P, Lei X, Liu X,Wang H, Lu L, Xiong T, Li D, Zhu Z, Duan E, Jiang E, Han M, Xu Y, Wang F, Zhou J*. MSX2 mediates entry of human pluripotent stem cells into mesendoderm by simultaneously suppressing SOX2 and activating NODAL signaling. Cell Res. 2015 Dec;25(12):1314-32. (IF=14.812)