刘玉英，1978年生，籍贯山东荣成，肿瘤免疫学家，中国医学科学院基础医学研究所研究员，博士生导师。先后师从于军事医学科学院吴祖泽院士与中国医学科学院药物研究所胡卓伟教授，从事分子免疫和肿瘤药理学研究。博士毕业后，在美国南卡罗来纳州医科大学进行六年博士后研究，主要从事肿瘤生物学方面研究。2014年回国后，加入中国医学科学院基础医学研究所，2022年升为助理研究员。

肿瘤免疫、肿瘤免疫治疗、生物机械力肿瘤免疫、肿瘤休眠。

1. Lv J#, Liu Y#, Mo S#, Zhou Y, Chen F, Cheng F, Li C, Saimi D, Liu M, Zhang H, Tang K, Ma J, Wang Z, Zhu Q, Tong WM, Huang B*. Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Nat Cell Biol. 2022;24(3):364-372. (IF=22.198)

2. Liu Y#, Zhou N#, Zhou L#, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B*. IL-2 regulates tumor-reactive CD8 + T cell exhaustion by activating the aryl hydrocarbon receptor. Nat Immunol. 2021;22(3):358-369. (IF=23.205)

3. Lv J#, Liu Y#, Cheng F#, Li J, Zhou Y, Zhang T, Zhou N, Li C, Wang Z, Ma L, Liu M, Zhu Q, Liu X, Tang K, Ma J, Zhang H, Xie J, Fang Y, Zhang H, Wang N, Liu Y* and Huang B*. Cell softness regulates tumorigenicity and stemness of cancer cells. EMBO J. 2021;40(2):e106123. (IF=10.905)

4. Liu Y*#, Zhang T#, Zhang H#, Li J, Zhou N, Fiskesund R, Chen J, Lv J, Ma J, Zhang H, Tang K, Cheng F, Zhou Y, Zhang X, Wang N and Huang B*. Cell Softness Prevents Cytolytic T-cell Killing of Tumor-Repopulating Cells. Cancer Res. 2021;81(2):476-488. (IF=10.269, ESI, F1000)

5. Liu Y#, Lv J#, Liu J, Li M, Xie J, Lv Q, Deng W, Zhou N, Zhou Y, Song J, Wang P, Qin C, Tong WM, Huang B*. Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19. Cell Res. 2020;30(12):1078-1087. (IF=17.916)

6. Gao Y#, Zhang H#, Zhou N#, Xu P, Wang J, Gao Y, Jin X, Liang X, Lv J, Zhang Y, Tang K, Ma J, Zhang H, Xie J, Yao F, Tong W, Liu Y*, Wang X*, Huang B*. Methotrexate-loaded tumour-cell-derived microvesicles can relieve biliary obstruction in patients with extrahepatic cholangiocarcinoma. Nat Biomed Eng. 2020;4(7):743-753. (IF=18.044)

7. Liu Y#, Fang Y#, Chen X#, Wang Z, Liang X, Zhang T, Liu M, Zhou N, Lv J, Tang K, Xie J, Gao Y, Cheng F, Zhou Y, Zhang Z, Hu Y, Zhang X, Gao Q, Zhang Y, Huang B*. Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome. Sci Immunol. 2020;5(43):eaax7969. (IF=11.996, C100)

8. Liu Y#, Liang X#, Dong W#, Fang Y, Lv J, Zhang T, Fiskesund R, Xie J, Liu J, Yin X, Jin X, Chen D, Tang K, Ma J, Zhang H, Yu J, Yan J, Liang H, Mo S, Cheng F, Zhou Y, Zhang H, Wang J, Li J, Chen Y, Cui B, Hu ZW, Cao X, Xiao-Feng Qin F, Huang B*. Tumor-Repopulating Cells Induce PD-1 Expression in CD8⁺ T Cells by Transferring Kynurenine and AhR Activation. Cancer Cell. 2018;33(3):480-494.e7. (IF=24.400, F1000, C100)

9. Liu Y#, Lv J#, Liu J#, Liang X, Jin X, Xie J, Zhang L, Chen D, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Jia Q, Zhu B, Kong Y, Guo J, Zhang H, Hu ZW, Cao X, Qin FX, Huang B*. STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells. J Clin Invest. 2018;128(3):1057-1073. (IF=12.87)

10. Liu Y#, Lv J#, Liang X#, Yin X, Zhang L, Chen D, Jin X, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Xie J, Wang N, Huang B*. Cancer Res. 2018;78(14):3926-3937. (IF=8.936)