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阜外医院

个人简介

吴永健,1965年生,籍贯山东临沂,心血管病专家,中国医学科学院阜外医院主任医师,博士生导师。1983年考入山东大学医学院临床医学专业,1988年获得学士学位。1994年在中国协和医科大学内科学专业攻读博士学位,从事心血管疾病研究。1996年进入德国Giessen大学从事博士后研究工作,从事心血管疾病基础研究。 2004年晋升为主任医师。


主要研究方向

主要从事冠心病和老年瓣膜性心脏病介入治疗及其相关研究。从事冠心病的临床和基础研究,年冠脉支架植入手术>1000例。我国最早开展经导管主动脉瓣膜置换手术(TAVR)的专家之一,目前致力于我国国产TAVR瓣膜设计和研发。


代表性成果

1.Lv J#, Ye Y, Li Z, Zhang B, Liu Q, Zhao Q, Zhao Z, Wang W, Zhang H, Duan Z, Wang B, Yu Z, Guo S, Zhao Y, Gao R, Xu H*, Wu Y*. Prognostic Value of Modified Model for End-Stage Liver Disease Scores in Patients With Significant Tricuspid Regurgitation. Eur Heart J Qual Care Clin Outcomes. 2022 May 24:qcac027. (IF=7.0635)

2. Guo S#, Zhang E, Zhang B, Liu Q, Meng Z, Li Z, Wang C, Gong Z, Wu Y*. Identification of Key Non-coding RNAs and Transcription Factors in Calcific Aortic Valve Disease. Front Cardiovasc Med. 2022 Jun 29;9:826744. (IF=5.846)

3. Guo S#, Zhang B,# Ye Y, Li Z, Liu Q,Zhao Z, Wang W, Yu Z, Zhang H, Zhao Q, Duan Z, Lv J, Zhang E,Wang B, Zhao Y, Gao R, Xu H* andWu Y*.Prognostic Value of Blood Pressure and Resting Heart Rate in Patients with Tricuspid regurgitation. Front. Cardiovasc. Med. 2022. 9:937412. (IF=5.846)

4. Zhang H#, Zhao Z, Yao J, Zhao J, Hou T, Wang M, Xu Y, Wang B, Niu G, Sui Y, Song G,Wu Y*. Prior Percutaneous Coronary Intervention and Outcomes in Patients after Coronary Artery Bypass Grafting: A Meta-Analysis of 308,284 Patients. Ther Adv Chronic Dis. 2022 May 13;13:20406223221078755. (IF=4.9696)

5. Zhao Q#, Zhang B, Ye Y, Li Z, Liu Q, Zhao R, Zhao Z, Wang W, Yu Z, Zhang H, Duan Z, Wang B, Lv J, Guo S, Zhao Y, Gao R, Xu H*, Wu Y*. Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Moderate Aortic Regurgitation: Potential Implications for Treatment Decision-Making. Front Cardiovasc Med. 2022 Jan 17;8:800961. (IF=5.846)

6. Zhao Q#, Xu H, Liu Q, Ye Y, Zhang B, Li Z, Gao R, Wu Y*. Therapeutic Decision-Making and Outcomes in Elderly Patients With Severe Symptomatic Aortic Stenosis: Prognostic Implications of Elderly Patients' Initial Decisions. Front Cardiovasc Med. 2021 Jul 26;8:696763. (IF=5.846)

7. Yu Z#, Zhao Q, Ye Y, Wang M, Zhou Z, Zhang H, Zhao Z, Liu Q, Zhang Z, Wu Y*, Xu H*. Comprehensive Geriatric Assessment and Exercise Capacity in Cardiac Rehabilitation for Patients Referred to Transcatheter Aortic Valve Implantation. Am J Cardiol. 2021 Nov 1;158:98-103. (IF=3.1333)

8. Zhang B#, Xu H, Zhang H, Liu Q, Ye Y, Hao J, Zhao Q, Qi X, Liu S, Zhang E, Xu Y, Gao R, Pibarot P, Clavel MA*, Wu Y*; CHINA-DVD Collaborators. Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide in Elderly Patients With Valvular Heart Disease. J Am Coll Cardiol. 2020 Apr 14;75(14):1659-1672. (IF:27.2030)

9. Wang Y#, Wang M, Song G, Wang W, Lv B, Wang H, Wu Y*. Optimal Pre-TAVR Annulus Sizing in Patients with Bicuspid Aortic Valve: Area-derived Perimeter By CT Is The Best-correlated Measure with Intraoperative Sizing. Eur Radiol. 2019 Jan;29(1):259-269. (IF=7.034)

10. Das S#, Zhang E#, Senapati P, Amaram V, Reddy MA, Stapleton K, Leung A, Lanting L, Wang M, Chen Z, Kato M, Oh HJ, Guo Q, Zhang X, Zhang B, Zhang H, Zhao Q, Wang W, Wu Y*, Natarajan R*. A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells. Circ Res. 2018 Dec 7;123(12):1298-1312. (IF=23.2125)